Endocrine Abstracts

Introduction: In primary hypothyroidism, the increase in TRH may cause hyperplasia in the pituitary gland. It has been reported that long-standing hypothyroidism might also cause irreversible pituitary damage, which may lead to a deficiency in one or more pituitary hormones. Herein, we report a case with primary autoimmune hypothyroidism causing pituitary enlargement mimicking pituitary macroadenoma and secondary adrenal insufficiency. Case: A 17-year-ol...

Introduction: Giant prolactinomas are rare tumors accounting for 2–16% of all prolactinomas. They may be aggressive and invasive. Rarely, they might not have a suprasellar component and grow downward. Such extension can make it difficult to distinguish pituitary adenoma from other skull base tumors. We present a case that was considered to be chordoma based on clinical and radiological imaging features, but was diagnosed as prolactinoma by pituitary biopsy.<p class="a...

Introduction: Coronavirus disease-19 (COVID-19) pandemic renders high morbidity and mortality. Glucocorticoid excess is characterized by increased susceptibility to infections due to impairment of the innate and adaptive immune system. Manifestations of Cushing disease (CD) including diabetes mellitus (DM), hypertension, and obesity are risk factors for severe COVID-19 disease. We present three CD patients with different clinical courses of COVID-19. The patients’ general...